This week’s digest covers 10 papers: 6 African-led studies from journals like Biotechnology and Bioengineering, Geoheritage, and Biomedicines, and 4 global studies from Living Reviews in Computational Astrophysics, Journal of the Korean Physical Society, Sociological Methodology, and Computational Biology and Chemistry. This week: engineered alpha-1-antitrypsin matches plasma-derived version, Oyo State’s geoheritage potential, open-source hypoxia system, AI in stem cell trends, sleep deprivation model comparison, new lifetime distribution, neutron star evolution, AdS black hole entropy, residualized quantile regression, and adversarial validation of gene perturbations.